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In Molecular Diagnosis of Infectious Diseases leading international authorities provide a comprehensive and up-to-date set of basic and advanced methods that illuminate the principles of molecular diagnostics and allow researchers to establish assay systems tailored to their specific needs. This unique collection of protocols covers the latest strategies for identifying novel diagnostic markers, epitope mapping, and the production and purification of recombinant antigens, as well as their use as diagnostic reagents in immunological assays. It also includes promising techniques based on recent developments in antibody engineering and on the use of biosensors. Molecular Diagnosis of Infectious Diseases offers clinical microbiologists, clinical chemists, and pathologists unique tools with which to develop improved assays for diagnosing infectious diseases. The book is certain to play a leading role in helping researchers to understand and realize in their daily work the powerful potential of molecular diagnostic techniques in clinical microbiology today.
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In Hepatitis C Protocols, Johnson YN Lau and his expert collaborators present cutting-edge techniques for study of the hepatitis C virus infection and its disease, hepatitis C, which afflict an estimated 170 million people worldwide. The methods range from the detection of anti-HCV in serum and HCV in liver tissue, to HCV genotyping and the detection and quantification of HCV in serum. In addition to these key protocols, the authoritative contributors also evaluate recombinant proteins in immunological test systems, including the identification of important antigenic epitopes, antibodies, and recombinant antigens. Molecular and immunological techniques to study this virus and its infection, as well as animal models and recombinant virus technology commonly used to express hepatitis C viral proteins, are also developed. Hepatitis C Protocols summarizes the state-of-the-art in today's research and understanding of the virology of hepatitis C virus. The methods and systems detailed in this book will play a key role in the development of more effective antivirals, in the development of vaccines, and in a deeper understanding of viral replication strategies, viron structure, and the mechanisms of viron assembly and release. A valuable new standard resource for all researchers and clinicians, Hepatitis C Protocols leads the way toward improved prevention, diagnosis, and treatment of viral hepatitis C.
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Communicable Diseases --- Communicable diseases. --- Emerging infectious diseases. --- Epidemiology.
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